Team 2
Cerebellar
Neurophysiology
Team description
Linking synapses to behavior: decoding cerebellar computations in action
Our team investigates the role of the cerebellum in sensorimotor integration, from synaptic mechanisms to systems-level function.
We study the biophysical mechanisms underlying synaptic transmission and how they are integrated within cerebellar cortex microcircuits.
Our research focuses in particular on how these processes support sensorimotor integration in awake behaving animals.
Building on recent work, we are developing and applying advanced optical tools to probe cerebellar function across scales.
We combine expertise in electrophysiology, optical imaging, and behavioral approaches to analyze cerebellar activity from single synapses to neuronal populations in mice performing cerebellar-dependent tasks.
Research areas : Cerebellar physiology – Sensorimotor integration – Synaptic transmission – Microcircuit dynamics – Systems neuroscience – In vivo imaging
Research Topics
Spinal motoneuron excitability is homeostatically regulated through β-adrenergic neuromodulation in wild-type and presymptomatic SOD1 mice.
Antonucci S, et al.
Progress in Neurobiology | 2026
Motoneurons Inhibitory Synapses Homeostatically Respond to Neuronal Activity and Modulate Amyotrophic Lateral Sclerosis Pathogenesis.
Halablab K, et al.
The Journal of Neuroscience | 2026
Repetitive Trans-spinal magnetic stimulation Promotes Repair in Inflammatory Spinal Cord Injury Through Sex-Dependent Immune Modulation
Semprez F, et al.
The Journal of Neuroinflammation | 2026
Prolonged Repetitive Trans-Spinal Magnetic Stimulation Promotes Superior Functional Recovery After Severe Spinal Cord Injury in Rats
Garrido E, et al.
The Journal of Neurotrauma | 2026
Decoding Wetting Behavior: Capillary Rise Experiments with Amphiphilic Compounds and Theoretical Aspects
Hamraoui A, et al.
Langmuir | 2025
Spinal cord injury alters the therapeutic potential of olfactory ensheathing cells harvested in an autologous transplantation model
Delarue Q, et al.
Stem Cell Research & Therapy | 2025
The alpha7 nicotinic acetylcholine receptor mediates network dysfunction in a mouse model of local amyloid pathology
Koukouli F, et al.
Molecular Psychiatry | 2025
Renshaw cells, corelease and nicotinic receptors: The last journey in synaptic transmission
Lamotte d’Incamps B
Neuroscience | 2025
Involvement of the Endothelial N-Methyl-D-Aspartate Receptor on Vessel-Associated Positioning and Differentiation of Cortical Oligodendrocytes and on Motor Activity
Beranger A, et al.
The Journal of Neuroscience | 2025
KCC2 enhancers normalize reflex responses and improve locomotor function after chronic spinal cord injury
Bilchak JN, et al.
The Journal of Physiology | 2025
