Team 8
Orientation and
Coordination

Team description

From movement to navigation: decoding how brain circuits guide behavior

Our team investigates how neural circuits support motor control and spatial orientation in the intact brain.
We study the mechanisms by which cerebellar circuits enable adaptive and precise movements, as well as how multisensory information is integrated to build internal representations of space.

Our research focuses in particular on cerebellar contributions to motor learning and on head-direction circuits involved in spatial navigation.
We also explore how neuronal populations encode, predict, and update behavioral outputs in real time

We combine expertise in behavioral paradigms, neural recordings, optogenetics, and computational approaches to link circuit dynamics to behavior in freely moving animals.

Research areas : Motor control – Cerebellum – Spatial navigation – Multisensory integration – Neural circuits – Behavioral neuroscience

Spinal motoneuron excitability is homeostatically regulated through β-adrenergic neuromodulation in wild-type and presymptomatic SOD1 mice.

Antonucci S, et al.

Progress in Neurobiology | 2026

Motoneurons Inhibitory Synapses Homeostatically Respond to Neuronal Activity and Modulate Amyotrophic Lateral Sclerosis Pathogenesis.

Halablab K, et al.

The Journal of Neuroscience | 2026

Repetitive Trans-spinal magnetic stimulation Promotes Repair in Inflammatory Spinal Cord Injury Through Sex-Dependent Immune Modulation

Semprez F, et al.

The Journal of Neuroinflammation | 2026

Prolonged Repetitive Trans-Spinal Magnetic Stimulation Promotes Superior Functional Recovery After Severe Spinal Cord Injury in Rats

Garrido E, et al.

The Journal of Neurotrauma | 2026

Decoding Wetting Behavior: Capillary Rise Experiments with Amphiphilic Compounds and Theoretical Aspects

Hamraoui A, et al.

Langmuir | 2025

Spinal cord injury alters the therapeutic potential of olfactory ensheathing cells harvested in an autologous transplantation model

Delarue Q, et al.

Stem Cell Research & Therapy | 2025

The alpha7 nicotinic acetylcholine receptor mediates network dysfunction in a mouse model of local amyloid pathology

Koukouli F, et al.

Molecular Psychiatry | 2025

Renshaw cells, corelease and nicotinic receptors: The last journey in synaptic transmission

Lamotte d’Incamps B

Neuroscience | 2025

Involvement of the Endothelial N-Methyl-D-Aspartate Receptor on Vessel-Associated Positioning and Differentiation of Cortical Oligodendrocytes and on Motor Activity

Beranger A, et al.

The Journal of Neuroscience | 2025

KCC2 enhancers normalize reflex responses and improve locomotor function after chronic spinal cord injury

Bilchak JN, et al.

The Journal of Physiology | 2025